Unlocking the Secrets of Clinical Strategy: Lessons from Alex Tang, MBA, PA-C, on Bridging Business and Medicine

In the ever-evolving landscape of U.S. healthcare, “clinical strategy” is fast emerging as a must-have leadership discipline—one that demands fluency in both the art of patient care and the science of business operations. Yet for many, the term remains unclear, often dismissed as just another buzzword. Why does clinical strategy matter now? Because healthcare organizations face relentless pressure to deliver better outcomes, control costs, and drive innovation—often all at once. With systems stretched by COVID-19, workforce shortages, and shifting reimbursement models, leaders must fuse clinical expertise with business acumen to survive and thrive.

That’s exactly what Alex Tang, MBA, PA-C, Vice President of Clinical Strategy & Innovation at CareAbout, brings to the table. In our conversation, Alex draws from his journey as a trauma and neurosurgery physician assistant, primary care clinician, business school graduate, and health system executive, giving us a blueprint for how clinical strategy works in real life. If you want to understand how to implement strategy that actually moves the needle—instead of stalling in the C-suite—Alex’s story offers both inspiration and practical steps.

What Is Clinical Strategy, and Why Is It Gaining Traction?

Clinical strategy is the intentional integration of clinical knowledge, business principles, and population health management to drive both patient and organizational outcomes. In the words of Alex Tang, “Clinical strategy essentially is an interchangeable term. I would say it’s similar to population health. It entails a lot of understanding not only the healthcare business side but also the clinical aspect of it and population health management as well.” In short, clinical strategy bridges the gap between medicine and management, leaning more toward business but leveraging a strong foundation in direct patient care.

Why is this relevant today? U.S. health systems are at an inflection point. They must:

• Transition to value-based care models.

• Navigate physician shortages and workforce burnout.

• Integrate technology (from EHRs to telemedicine) into workflows.

• Respond to population health imperatives, including social determinants of health.

• Satisfy both regulatory and payer demands on quality and cost.

Leaders can’t afford to silo clinical and business functions anymore. As Alex explains, “It’s a really unique blend… you have to leverage clinical experience, but also business school knowledge. The MBA is a good framework, but the hands-on, on-the-ground experience is just as vital.”

How Does a Clinician Become a Clinical Strategist?

Becoming a clinical strategist is a process of broadening one’s scope from bedside care to systems thinking, and intentionally layering business expertise onto a clinical foundation. Alex’s own path is instructive. He began with a decade of hands-on clinical work:

1. Surgery and Trauma: “The first five years of my career were spent in a public hospital system… I trained with the best surgeons around in the trauma field and really learned how to manage critical care.”

2. Neurosurgery: “I moved next to NYU Health, where I developed tactical skills in neurosurgery.”

3. Primary Care, Asian Community Focus: “I spent five years in primary care, part-time in the Asian community. I wanted to learn about managing healthcare needs across cultures and settings.”

Alex emphasizes the importance of being “well-rounded”: “As a PA, we’re trained to be well-rounded. But to get perspective, I needed to move beyond one field… hopping into primary care allowed me to get perspectives I didn’t have.”

The pivot to strategy came after hitting a career ceiling: “At a certain point, you hit ceilings. It’s not that I was a master at my prior skills, but I wanted to learn more about how the health world works.” That meant business school, networking, and, crucially, operational leadership in independent physician associations (IPAs) and management services organizations (MSOs).

Key steps to becoming a clinical strategist:

• Accumulate broad clinical experience—across settings, patient populations, and clinical roles.

• Pursue formal education in business, finance, or healthcare administration.

• Build relationships and networks outside your immediate clinical sphere.

• Step into roles that require both clinical and operational oversight (e.g., IPAs, MSOs, ACOs).

What Do Clinical Strategists Actually Do? (And Why Does It Matter?)

Clinical strategists translate clinical realities into scalable, sustainable business models—often under immense uncertainty. In practice, this means:

• Leading population health initiatives and quality improvement projects.

• Designing, implementing, and optimizing care delivery programs (e.g., house calls, mobile testing).

• Negotiating with payers and providers to improve contract terms for clinicians and organizations.

• Integrating clinical, operational, and financial data to guide decision-making.

Alex recounts his work building a mobile COVID-19 testing program as a case study:
“The board came together and basically said, ‘Hey, we want to do testing, and we want it to be mobile.’ We didn’t have the resources for it… So we backtracked: What are the components? How do we protect staff? What precautions do we need? We started with research, built a prototype in a parking lot, leveraged partnerships, and operationalized the program.”

Clinical strategists matter because they:

• Break down silos between business and clinical staff.

• Spot operational risks and clinical blind spots before they impact outcomes.

• Accelerate change management by “speaking both languages.”

• Foster buy-in from front-line staff, not just senior leadership.

What Skills Set Clinical Strategists Apart?

The core skills of a clinical strategist are resilience, systems thinking, adaptability, and a bias for action. Alex credits his background in trauma surgery with developing his “Mamba mentality”—a term borrowed from Kobe Bryant’s legendary approach to relentless improvement:

• “The skills of not fearing failure, of trying multiple times on certain things but not succeeding and keeping on trying… It’s a go-to attitude. Half the battle is having the audacity to attempt to solve that problem.”

• “In trauma, there are so many people involved, everyone has distinct roles… I was able to play all those roles. If a role is missing, I can take on that role. It’s about clear delineation and fitting into a system.”

To develop these skills:

• Don’t fear “small” roles—every contribution matters.

• Learn to predict organizational needs 1-3 years ahead.

• Take initiative in undefined or ambiguous situations.

• Cultivate operational and clinical allies; build trust across departments.

• Treat business operations with the urgency and clarity of clinical emergencies—without succumbing to panic.

How Can Organizations Better Execute Strategy? (Hint: It’s Not Top-Down)

The single biggest barrier to successful strategy execution is a lack of buy-in from those actually doing the work. Alex is unequivocal:

• “Does the project fit the organization’s mission and vision? Is everyone aligned? Do you have strong buy-in—not just from leaders above, but from those below?”

• “Often what I see is executives who are sold on a project, and then it ends up not working because they’re not the only players in the game.”

To close the gap between strategy and operations:

1. Ensure Mission Alignment: Every project should map directly to organizational goals.

2. Secure Front-Line Buy-In: If staff don’t see the value, reframe or rethink the project.

3. Integrate Clinical and Business Perspectives: Find the middle ground; sometimes the business case makes sense but isn’t clinically practical.

4. Communicate Outcomes, Not Just Processes: Sell the “why”—how this work will benefit patients, staff, or community.

Alex’s practical advice: “If you’re adding more work, that’s fine—but is there a good outcome at the end? Start selling that part. In healthcare, you’re always helping people, but you have to reinforce that message.”

How Can Non-Clinical Executives Bridge the Clinical Divide?

Non-clinical executives need trusted clinical allies—ideally those with business savvy—to bridge the gap. Alex’s prescription:

• “You need to have really strong clinical allies, and not just clinical but those who also have business experience, such as myself.”

• “Often, clinicians will always… there’s a lot of pride within the profession, especially between patient and clinician. When you start disrupting that, you start losing support.”

How to identify and cultivate clinical allies:

• Look for clinicians who mentor others and aspire to leadership.

• Invest in leadership development for clinicians—sponsor MBAs, fellowships, and rotations in administrative functions.

• Involve clinicians early in the design and rollout of strategic initiatives.

• Build “hybrid” roles that formalize this dual expertise.

Alex’s takeaway: “Healthcare is a business and an engine that needs to keep running, but you need clinicians who understand that to drive the business or be tied intimately to the business leaders making decisions.”

What Can Early-Career Professionals Do to Develop “Mamba Mentality”?

Anyone can cultivate the courage and adaptability needed to drive clinical strategy—but it requires deliberate practice and mindset shifts. Alex suggests:

• “There’s no role that’s too small, and your limitation is what you define it.”

• Proactively define and shape your role, especially in new or ambiguous settings.

• Get to know your organization’s mission, vision, and 1-3 year strategy.

• Look for ways to integrate your work with, not duplicate, what others are doing.

• Practice leadership in small groups or volunteer settings—Alex’s story about bringing a basketball to Chinese school to foster connection is a reminder that leadership starts informally.

Key Takeaways: Leading the Future of Healthcare Requires Clinical Strategy

Healthcare’s most urgent challenges—cost containment, patient experience, care delivery innovation—can’t be solved by business or clinical minds alone. Clinical strategy, as exemplified by leaders like Alex Tang, MBA, PA-C, is about blending the best of both worlds. If you’re a business leader, invest in clinical relationships. If you’re a clinician, seek opportunities to build business acumen. And if you want to lead the next wave of healthcare transformation, remember Alex’s advice: “Your limitation is what you define it. You have to have the audacity to try.”

Actionable Insight:
Take inventory of your current leadership team and project workgroups. Where are the “bridges” between clinical and business? Where are the silos? Challenge yourself to identify at least one area where a clinical strategist—or “Mamba mentality”—could unlock better results. If you don’t have such a bridge, it’s time to build one. As U.S. healthcare continues to transform, the leaders who thrive will be those who master the art and science of clinical strategy.

Alex Tang, MBA, PA-C, is Vice President of Clinical Strategy & Innovation at CareAbout. This conversation was hosted by Cole Lyons for The American Journal of Healthcare Strategy.